LiDCO Group Plc 01 June 2005 For immediate release 1 June 2005 LiDCO GROUP PLC ("LiDCO" or "the Company") Positive Data Presented A New Application for LiDCO's Minimally Invasive Monitoring System 1 June 2005: LiDCO Group plc (AIM: LID), the cardiovascular monitoring company, is pleased to announce that positive data was presented at the Society of Obstetric Anesthesia and Perinatology meeting held in Palm Springs, California, USA. Doctors at the Departments of Anesthesiology & Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio, TX reported that the LiDCOplus Monitor, used to observe cardiovascular changes during continuous epidural anesthesia in a patient undergoing caesarean section, was able to safely maintain cardiac output and blood pressure monitoring where this otherwise would not have been possible without the use of an invasive catheter. This department is one of a number of University centers actively investigating the potential applications of the LiDCO technology to the anesthetic management of high risk obstetric patients. Investigator, Dr McGrane, concluded: "We feel that the LiDCO monitoring system was a safe, effective, minimally invasive alternative which allowed us to avoid the risks associated with placement of a PA catheter, and through continuous hemodynamic monitoring allowed implementation of epidural anesthesia with confidence, thus avoiding the risks of general anesthesia in this parturient." Dr Terry O'Brien, LiDCO' s Chief Executive, commented: "This is the first report of the use of our minimally invasive monitoring in the high risk obstetric population. We are very encouraged by these early results and particularly excited that a number of other University centers are investigating the use of our device to improve care and outcomes in the late stages of high risk pregnancy and in life threatening conditions such as pre-eclampsia." For further information please contact: LiDCO Group Plc Terry O'Brien (CEO) terry@lidco.com 020 7749 1500 Hugh McGarel-Groves (FD) hugh.mcgarelgroves@lidco.com Buchanan Communications Tim Anderson, Mary-Jane Johnson, James Strong 020 7466 5000 Notes for Editors About LiDCO Plc LiDCO is a UK-based AIM-traded developer, manufacturer and leading supplier of minimally invasive, computer-based hemodynamic monitoring equipment and disposables used primarily for the management of critical care and cardiovascular risk hospital patients. Use of LiDCO's technology has been shown to significantly reduce the complications (particularly infections) and costs associated with major surgery. The technology was invented in the Department of Applied Physiology based at St Thomas' Hospital, London where the Company maintains a research base. The Company's manufacturing facility is in Hoxton, London and its current products are: • LiDCOplus and PulseCO monitors: computer-based platforms for displaying a range of real-time, continuous hemodynamic parameters including cardiac output, oxygen delivery and fluid volume; • LiDCO disposables: used in conjunction with the LiDCOplus Monitor accurately determine cardiac output in a minimally-invasive manner. Distribution Network: The Company has now achieved registration of its products in 13 markets in Europe, the USA, Brazil and Japan. It sells direct to the NHS in the UK, and through a worldwide network of specialty critical care distributors. Background to the recently published clinical trial: Better than standard care - (EGDT) improves outcome in high risk surgery patients: The results of a major trial at St George's Hospital, London using LiDCO's minimally invasive monitoring technology were presented during the 25th International Symposium on Intensive Care and Emergency Medicine in Brussels (21st to 25th March). The results have revealed the following: a) Savings in the cost of treating patients amounting to an average of £4,000 per patient. Extrapolated nationally, this would equate to a saving of £500 million per annum for the NHS b) The monetary saving (£248,000) - resulted from 640 hospital days saved for 62 patients, an average of more than 10 bed days per patient c) The savings in cost and hospital days were associated with a significant reduction in medical complications (particularly infections - which were halved) through the use of LiDCO's minimally invasive technology to improve tissue oxygen levels following surgery. This information is provided by RNS The company news service from the London Stock Exchange