LiDCO Group Plc 30 March 2005 For immediate release 30 March 2005 LiDCO GROUP PLC ("LiDCO") Lithium Chloride Mutual Recognition Approval in Denmark LiDCO Group plc, (AIM: LID) the UK-based cardiovascular monitoring company, is pleased to announce today that a further European approval of Lithium Chloride for use with the LiDCOplus System has been granted in Denmark. Lithium Chloride is used in conjunction with the LiDCOplus System to provide an absolute measure of a patients cardiac output. This latest registration now provides LiDCO with full marketing approval in a portfolio of thirteen European countries including UK, Spain, Germany, Austria, Italy, Czech Republic, Belgium and Holland, Ireland, Norway, Sweden, Bulgaria and Denmark. Commenting on the approval in Denmark, Dr Terry O'Brien, LiDCO's CEO, said: "Following on from the recent approvals in Ireland, Norway, Sweden and Bulgaria we have now registered the lithium chloride injection as a pharmaceutical (in-vivo diagnostic) in a further European market. Europe is the most developed territory for the adoption of advanced minimally invasive cardiovascular monitoring and with this extended group of territories we expect the growth in European sales to be further accelerated in 2005." For further information please contact: LiDCO Group Plc Terry O'Brien (CEO) terry@lidco.com 020 7749 1500 Buchanan Communications Tim Anderson, Mary-Jane Johnson, James Strong 020 7466 5000 Notes for Editors LiDCO is a leading developer of minimally invasive, computer-based hemodynamic monitoring equipment and disposables used primarily for the management of critical care and cardiovascular risk hospital patients. The Company's current products are: • the LiDCOplus and PulseCO monitors, computer-based platforms for displaying a range of real-time continuous hemodynamic parameters including cardiac output, oxygen delivery and fluid volume; and • the LiDCO disposable for accurately determining cardiac output in a minimally-invasive manner. Lithium dilution calibrated waveform analysis The LiDCOplus monitor uses arterial pressure waveform analysis, in conjunction with Lithium dilution cardiac output calibration. Lithium does not occur naturally in the body. Making this a patentable reference indicator. The injected lithium is used in trace amounts as an in vivo diagnostic, not a therapeutic drug, to calibrate the PulseCO continuous beat to beat software. The measurement of the marker lithium ion concentration in blood is made through a proprietary lithium selected ion sensor attached to existing radial or other peripheral arterial lines. The lithium is injected into the venous circulation via a central venous or peripheral venous line. The lithium cardiac output determination is then used to calibrate cardiac output continuously from the arterial pulse power profile of the pressure waveform. This information is provided by RNS The company news service from the London Stock Exchange