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Press Release |
27 November 2012 |
("LiDCO" or the "Company")
Multidisciplinary standardized clinical protocol using LiDCOrapid
shows improvement in patient outcomes
LiDCO Group Plc (AIM: LID), the cardiovascular monitoring company, welcomes a study published in the British Journal of Surgery, in which its LiDCOrapid hemodynamic monitor was used as part of a standardized clinical pathway to optimize patients, which has shown a significant improvement in patient outcomes. In particular, patients treated on the clinical pathway showed a significant reduction in length of hospital stay (by an average of ten days), immediate extubation and first-day mobilization following surgery.
Dr Terry O'Brien, CEO of LiDCO, commented: "Resources are being squeezed and healthcare systems are increasingly required to optimize their practice. I am delighted with the very significant results obtained in this study. The investigators used the LiDCOrapid monitor in this oesophagectomy clinical pathway for the fluid and drug management of patients undergoing a very demanding surgery, and materially improved patient outcomes.
LiDCO's ease of use facilitates the adoption of improvements in hospital processes that are increasingly shown to lead to better short-term outcomes. With its additional non-invasive functionality, the LiDCOrapid v2 with Unity software will be available shortly, further expanding the numbers of patients who can benefit."
Details of the study
The study took the standardized oesophagectomy clinical pathway ("SOCP") developed at the Department of Thoracic Surgery at Virginia Mason Medical Centre ("VMMC") in the US, and applied a similar pathway to patients undergoing oesophagectomy at the Royal Surrey County Hospital ("RSCH") in Guildford, UK. The objective was to see whether a SOCP could be transferred between hospitals to improve patient outcomes. Goal-directed fluid therapy using the LiDCOrapid intra operatively and for six hours post surgery was applied to all patients under the standardized care pathway at RSCH. Intraoperative fluid management is an established standard of care at RSCH.
Patients were grouped based on whether or not they were operated on under the SOCP (group 3 and group 1 respectively) and were compared with each other as well as compared with a US group who had been operated under the SOCP at VMMC (group 4). Patients in group 2 were operated on after the introduction of the SOCP but were not included in the pathway.
Fewer patients experienced postoperative complications following introduction of the clinical pathway (9 of 12 in group 1, versus 4 of 12 in group 3; P = < 0.041). Statistical analysis indicated that the SOCP was the only variable significantly associated with a reduced incidence of postoperative complications.
Significant improvements seen following implementation of the clinical pathway included the proportion of patients mobilizing on postoperative day 1 (1 of 12 in group
1 versus 12 of 12 in group 3; P < 0.001), median length of critical care stay (4 (range 2-20) versus 3 (1-5) days respectively; P < 0.001) and median length of hospital stay (17 (12-30) versus 7 (6-37) days; P = 0.022). Statistical analysis confirmed the SOCP to be the only variable significantly associated with a reduced length of hospital stay
Reference:
Preston, SR et al. (2012) Impact of multidisciplinary standardized clinical pathway on perioperative outcomes in patients with oesophogeal cancer. Br J Surg; DOI: 10.1002/bjs.8974
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For further information, please contact:
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LiDCO Group Plc |
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Terry O'Brien (CEO) |
Tel: +44 (0)20 7749 1500 |
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Paul Clifford (Finance Director) |
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John Rowland (Company Secretary) |
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finnCap |
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Geoff Nash / Henrik Persson Stephen Norcross (broking) |
Tel: +44 (0)20 7600 1658 |
Media enquiries:
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Abchurch |
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Adam Michael / Joanne Shears / Simone Elviss Jamie Hooper |
Tel: +44 (0) 20 7398 7728 |
About LiDCO Group Plc
LiDCO is a supplier of minimally invasive hemodynamic equipment to hospitals, to monitor the amount of blood flowing around the body and ensure that vital organs are adequately oxygenated. LiDCO's products facilitate the application of hemodynamic optimization protocols for high risk patients in both critical care units and in the operating theatre.
Increasingly clinical studies are showing that the optimization of patients' hemodynamic status in high risk patients produces better outcomes and reduced hospital stay. LiDCO's computer-based technology, developed at St Thomas' Hospital in London, has been shown to significantly reduce morbidity and complications, length of stay and overall costs associated with major surgery.
Key Products:
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LiDCOplus: a computer-based platform monitor used in the Intensive Care Unit for real-time continuous display of hemodynamic parameters including cardiac output, oxygen delivery and fluid-volume responsiveness (PPV% and SVV%) |
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LiDCOrapid: a cardiac output monitor designed specifically for use in the operating theatre for fluid and drug management. The monitor enables anesthetists to get accurate and immediate feedback on the patient's fluid and hemodynamic status - a key measure of overall well-being before, during and after surgery. The LiDCOrapid provides: |
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early and rapid warning of hemodynamic change to aid choice of therapeutic route: fluid or drug |
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quantification of hemodynamic response, |
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guidance on effective delivery of fluids to ensure the right amount at the right time |
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LiDCOview: an easy-to-use graphical display of historical LiDCOplus and LiDCOrapid hemodynamic data. |
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LiDCO Unity Software: The software incorporated into LiDCOrapid v2 will allow the LiDCOrapid monitor to co-display Covidien's level of consciousness parameter and add the convenience of CNSystem's continuous non-invasive blood pressure monitoring. This will address a growing requirement for non-invasive monitoring solutions that are more comprehensive and can effectively replace multiple single parameter monitors. |
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All LiDCO monitors use single-patient disposables (sensors or smartcards) which provide an ongoing revenue stream.
LiDCO Distribution Network:
LiDCO's strategy is to sell directly to hospitals in the UK, and through a network of specialty critical care and anesthesia distributors in the rest of the world.
LiDCO's sales office is in Cambridge, its manufacturing facility and headquarters are in London and its shares are traded on AIM. For more information please see www.lidco.com.